代谢综合征与腰椎间盘退变及其炎症因子的研究进展
摘要
腰椎间盘退变相关疾病（腰椎管狭窄症、退行性椎体滑移、椎间盘突出症）是腰痛的主要原因， 临床发病率高，探索椎间盘退变的影响因素有较大的临床意义。退行性椎间盘中炎症因子 IL-1β 和 TNF-α 水平升高是腰椎间盘退变的关键因素，研究发现代谢性疾病与椎间盘的退变有显著的联系，其中肥胖、糖尿病 等代谢性疾病与胸椎椎间盘退变有较强的相关性，同时具有一个或多个代谢性疾病的患者更容易发生椎间盘退 变，代谢综合征可能是引起退行性椎间盘炎症因子升高的始动因素，本文综述了代谢综合征与腰椎间盘退变及 其炎症因子的相关性，为腰椎间盘退变性疾病的预防和治疗提供新思路。参考
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